36 Endocrine System Trivia Questions

Welcome to our endocrine system trivia! 

This system plays a crucial role in regulating various bodily functions through the secretion of hormones. 

But how well do you understand this intricate system? 

Test your knowledge with these trivia questions and learn some fascinating facts along the way.

Let’s go. 

Endocrine System Trivia Questions

  1. What hormone, produced by the pineal gland, is often called the “sleep hormone” due to its role in regulating sleep-wake cycles?

  2. The adrenal glands produce several hormones, one of which is crucial for the body’s response to stress. Name this hormone.

  3. Which hormone, secreted by the thyroid gland, plays a significant role in regulating metabolism, heart rate, and body temperature?

  4. The pancreas serves both an exocrine and an endocrine function. For its endocrine role, name the two hormones it produces that regulate blood sugar levels.

  5. What is the name of the condition characterized by excessive production of cortisol, often leading to obesity, high blood pressure, and changes in skin appearance?

  6. Identify the master gland of the endocrine system that regulates other endocrine glands and is located at the base of the brain.

  7. Name the hormone responsible for stimulating milk production in the breasts after childbirth.

  8. Which hormone, produced by the parathyroid glands, plays a vital role in calcium homeostasis in the body?

  9. What is the name of the autoimmune condition where the immune system attacks the thyroid gland, often leading to hypothyroidism?

  10. GH (Growth Hormone) affects almost all tissues of the body by stimulating growth and regeneration. What is another name for GH?

  11. Which hormone, secreted by the adrenal medulla, is often termed the “fight or flight” hormone due to its effect on the sympathetic nervous system?

  12. What condition is characterized by the underproduction of thyroid hormones, leading to symptoms such as fatigue, weight gain, and sensitivity to cold?

  13. Name the hormone that raises blood calcium levels by encouraging bone resorption and is antagonistic to the hormone that lowers blood calcium levels.

  14. The Islets of Langerhans in the pancreas contain several types of cells that produce hormones. Which type of cell produces insulin?

  15. What syndrome is characterized by insulin resistance and is a common precursor to type 2 diabetes?

  16. Name the endocrine disorder caused by an overactive thyroid gland, which can lead to symptoms such as weight loss, increased appetite, and heat intolerance.

  17. Which hormone is primarily responsible for the regulation of the circadian rhythm and is secreted by the suprachiasmatic nucleus of the hypothalamus?

  18. Identify the hormone that increases the absorption of glucose and fatty acids and promotes protein synthesis, secreted by the anterior pituitary gland.

  19. What is the name of the hormone that prepares the body for childbirth by relaxing the ligaments in the pelvis and softening and widening the cervix?

  20. Which gland is known as the “third eye” in some vertebrates and is involved in regulating circadian rhythms and seasonal reproductive cycles?

  21. The zona glomerulosa of the adrenal cortex produces a hormone vital for regulating sodium and potassium balance. Name this hormone.

  22. What is the term for the cluster of symptoms that result from an excess of androgen hormones, often presenting in women?

  23. Name the hormone that increases the body’s metabolic rate, promotes alertness, quickens reflexes, and stimulates the fetal nervous system development.

  24. Which endocrine disorder is characterized by the growth of benign tumors in the endocrine glands, leading to an overproduction of hormones?

  25. Name the hormone secreted by the heart that helps regulate blood pressure and fluid balance by promoting sodium excretion and reducing blood volume.

  26. What is the name of the syndrome caused by excessive growth hormone in adults, leading to enlarged hands, feet, and facial features?

  27. Identify the hormone produced by adipose (fat) cells that helps to regulate energy balance by inhibiting hunger.

  28. Which hormone, secreted by the posterior pituitary gland, plays a crucial role in water balance and retention in the body?

  29. What is the primary function of the steroid hormone aldosterone in the kidney?

  30. Which condition is characterized by hyperglycemia due to the body’s inability to use insulin properly, often associated with obesity?

  31. Name the peptide hormone that stimulates contractions during childbirth and is also involved in lactation.

  32. What rare, life-threatening condition is caused by an extreme lack of thyroid hormone, often characterized by low body temperature, low blood pressure, and unconsciousness?

  33. Identify the hormone that promotes red blood cell production, primarily produced by the kidneys.

  34. Which hormone is responsible for the development and maintenance of male secondary sexual characteristics?

  35. What genetic disorder is characterized by a lack of functional receptors for androgens, leading to a resistance to male hormones?

  36. Name the disorder characterized by the overproduction of aldosterone, leading to hypertension and low potassium levels in the blood.


  1. Melatonin

  2. Cortisol

  3. Thyroxine (T4)

  4. Insulin and Glucagon

  5. Cushing’s Syndrome

  6. Pituitary Gland

  7. Prolactin

  8. Parathyroid Hormone (PTH)

  9. Hashimoto’s Thyroiditis

  10. Somatotropin

  11. Epinephrine (Adrenaline)

  12. Hypothyroidism

  13. Parathyroid Hormone (PTH)

  14. Beta cells

  15. Metabolic Syndrome

  16. Hyperthyroidism

  17. Vasoactive Intestinal Peptide (VIP)

  18. Insulin-like Growth Factor 1 (IGF-1)

  19. Relaxin

  20. Pineal Gland

  21. Aldosterone

  22. Polycystic Ovary Syndrome (PCOS)

  23. Thyroid Hormone

  24. Multiple Endocrine Neoplasia (MEN)

  25. Atrial Natriuretic Peptide (ANP)

  26. Acromegaly

  27. Leptin

  28. Antidiuretic Hormone (ADH), also known as Vasopressin

  29. To regulate the balance of salt and water by increasing sodium reabsorption in the kidneys.

  30. Type 2 Diabetes Mellitus

  31. Oxytocin

  32. Myxedema Coma

  33. Erythropoietin (EPO)

  34. Testosterone

  35. Androgen Insensitivity Syndrome (AIS)

  36. Primary Hyperaldosteronism, also known as Conn’s Syndrome

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